Levamisole: Applications & Adverse Effects.
Levamisole Hydrochloride, originally designed for veterinary uses, has now evolved into crucial in medical medicine. It is known by its CAS number 16595-80-5 and EINECS number 240-654-6. This compound is a pure white crystal powder, renowned for its potent anti-worm effects. It is mainly produced in China, conforming to rigorous USP/BP/EP standards.
Levamisole HCl stands out for its potency against Ascaris lumbricoides and hookworms. It is vital for both medical and veterinary health. However, knowing the possible Cas 16595-80-5 side effects and its proper application is crucial for secure care. This guide examines the significant uses, mechanisms, and negative effects of Levamisole HCl. It aims to provide a detailed reference for healthcare professionals and patients.
What is Levamisole HCl?
Levamisole HCl, often referred to as pure Levamisole HCl, is a crucial pharmaceutical substance. Its unique chemical structure, C11H12N2S·HCl, makes it a key player in drug intermediates. Identified by its CAS number, CAS 240-654-6, this substance is recognized by its exceptional purity level of 99%, guaranteeing both efficacy and reliability.
Produced from China, Levamisole HCl is renowned for its conformance to USP/BP/EP pharmacopeia criteria. These strict quality tests confirm its properties, including identification, dissolution, cleanliness, and assay results. Such parameters confirm its efficacy as an anthelmintic agent, vital for removing parasitic worms in both humans and animals.
Below is a detailed breakdown of Levamisole Hydrochloride’s essential features:
| Attribute | Specifications |
|---|---|
| Chemical Name | Levamisole Hydrochloride |
| Chemical Formula | C11H12N2S·HCl |
| Quality | 99% Levamisole HCl |
| Chemical Abstracts Service Number | CAS 240-654-6 |
| Origin | China |
| Purpose | Pharmaceutical Intermediates |
This strict quality control confirms that Levamisole HCl remains a reliable choice within the field of pharmaceutical intermediates.
Mode of Action of Levamisole
Levamisole Hydrochloride shows a complex mechanism that integrates immunomodulation and direct anthelmintic activity. This combined action makes it priceless in both medical and veterinary fields.
Immune Modulation
As an immune booster, Levamisole HCl enhances the immune system’s reaction. It activates various immune cells, aiding in the management of autoimmune diseases like rheumatoid arthritis. The method of function here involves improving T-cell function. This results in better immune surveillance and the elimination of pathogens.
Anti-Parasitic Properties
Levamisole HCl is known for its strong anthelmintic effects. Acting as a parasitic remover, it disrupts the neuromuscular system of parasitic worms. This causes paralysis and death, efficiently eliminating the infestation. As an anti-parasitic agent, Levamisole is subjected to stringent quality control. This guarantees its precision and potency in removing parasitic worms.
Main Uses of Levamisole HCl
Levamisole HCl has emerged as a multifaceted compound in both human and veterinary domains. Its purposes span from deworming to immunomodulatory therapies, impacting a broad spectrum of health and animal cases.
Healthcare Uses
In medical practice, Levamisole HCl is a potent parasitic remover, addressing parasitic worm infections. It is authorized for curing ascariasis and hookworm infections. Moreover, it plays a role in immunotherapy, improving the immune function in various diseases.
Animal Health Uses
For livestock, Levamisole HCl is essential in controlling parasitic infections. It guarantees the health and productivity of livestock and pets by eliminating harmful parasites. This compound is essential for cattle, sheep, goats, and household pets, fulfilling a key role in their overall health and wellbeing.
Quantity and Administration of Levamisole HCl
Levamisole is a versatile drug used in both human and animal health. It’s essential to know the right dosing and use methods for successful care and security.
Suggested Doses
The advised dose for using Levamisole is between 1.5 to 2.5 mg/kg of body weight. This guarantees the drug is potent and risk-free, minimizing the risk of adverse reactions. Quantity varies with patient age, weight, and the issue being treated.
Forms of Administration
Levamisole administration can be performed through various methods, depending on the patient or animal’s needs. Common forms consist of:
- Oral tablets
- Injectables
- Topical use (less common)
Usage Recommendations
When administering Levamisole HCl, it’s essential to follow the quantity guidelines. Here are some usage recommendations:
- Measure and administer the exact Levamisole dose as a medical expert recommends.
- Be aware of the different needs of species for correct administering Levamisole in veterinary settings.
- Speak with a veterinarian or medical expert to modify dosages considering patient reactions and side effects.
Below is a concise table listing the suggested doses for various species:
| Animal | Dose | Form |
|---|---|---|
| People | 2.5 mg/kg | Oral |
| Cows | 1.5-2.5 mg/kg | Shot |
| Ovines | 1.5-2.0 mg/kg | Oral |
Correct Levamisole administration guarantees treatment efficacy and lowers side effects. This causes better results for individuals and animals alike.
Likely Reactions of Levamisole
Levamisole Hydrochloride is widely recognized for its potency. However, it’s crucial to accept potential side effects. This guarantees they are quickly identified and addressed.
Common Side Effects
Gastrointestinal symptoms are among the most frequent CAS 136-47-0 adverse reactions. These include nausea, vomiting, and abdominal pain. Some individuals could also suffer from headaches. These symptoms, although typically mild, can be quite bothersome. They might cause ceasing the treatment or modifying the dose.
Severe Side Effects
Levamisole overdose can lead to critical health issues. A major concern is agranulocytosis, which dramatically decreases white blood cell counts. This makes patients very susceptible to infections. Other serious negative effects include vasculitis, which is inflammation of the blood vessels, and severe skin reactions such as rashes.
Doctors advise frequent supervision for any side effects to Levamisole HCl. Regular appointments and blood tests are suggested to avoid critical complications. This vigilant method is crucial to balance the treatment’s benefits against its risks.
Safety Measures and Warnings
When contemplating the use of Levamisole HCl, it is essential to adhere to certain cautions to guarantee health and safety. Patients should steer clear of Levamisole HCl if they have a recognized hypersensitivity to the compound or preexisting ailments such as liver or kidney disease. These are crucial Levamisole precautions to reduce any side effects.
Pregnant or breastfeeding mothers, as well as those with compromised immune systems, should talk to a medical expert before beginning care with Levamisole. This step is important for ensuring high levels of Levamisole safety. Additionally, regular blood tests might be necessary to observe the drug’s effects on the body, which further underscores the importance of being cautious.
It is equally important to comply with strict storage and handling guidelines to maintain the drug’s integrity and efficacy. Correct storage conditions include keeping Levamisole HCl in a cold, moisture-free place away from unfiltered sunlight. These Levamisole warnings are not to be ignored, as inappropriate handling can lead to reduced efficacy and likely risks.
| Issue | Step |
|---|---|
| Allergy | Do not use |
| Hepatic or renal issues | Consult healthcare provider |
| Expectant or nursing | Speak with medical expert |
| Compromised immune system | Speak with medical expert |
| Routine blood tests | Check compound effects |
| Keeping | Chilly, arid spot away from direct light |
Levamisole Hydrochloride in Animal Healthcare
Levamisole HCl is vital in veterinary healthcare, tackling parasitic diseases in livestock and pets. It boosts animal health and productivity when used correctly.
Usage in Livestock
In agriculture, Levamisole Hydrochloride is key to addressing parasitic infections in animals. As a strong Levamisole parasitic remover, it improves health and productivity in cattle, sheep, and pigs. The quantity must be precisely determined, based on the animal’s species and weight for best results and safety.
Safety for Pets
Securing pets’ safety with Levamisole HCl for pets is crucial. Veterinarians highlight the importance of correct identification and treatment plans to minimize adverse reactions. Detailed assessments assist decide if Levamisole veterinary is appropriate for each pet, guaranteeing their health and well-being.
Keeping and Managing of Levamisole HCl
Keeping Levamisole HCl appropriately is essential for its efficacy and safety. Levamisole HCl should be stored in airtight containers. It should be kept in a chilly, arid place, away from light, moisture, and pests. This confirms the drug stays strong and secure for longer.
Here are some instructions for handling Levamisole to preserve its pharmaceutical quality:
| Storage Parameter | Advice |
|---|---|
| Holder | Sealed, airtight |
| Heat Level | Ambient temperature (20-25°C) |
| Conditions | Chilly, dry, and without light |
| Humidity Management | Drying agents advised |
| Insect Control | Keep in insect-free location |
| Expiration Date | Stick to shelf life |
By adhering to these guidelines, Levamisole stays within the purity range required by pharmaceutical standards. Appropriate storage and handling of Levamisole maintains its efficacy for future use.
Differences with Other Medications
When differentiating Levamisole HCl with other therapies, it’s important to examine their unique clinical profiles and applications.
Levamisole HCl and Tetracaine
Levamisole and Tetracaine have completely distinct medical roles. Tetracaine is a potent local anesthetic, used to numb during medical procedures. It acts by blocking nerve signals, making it suitable for surgeries and minor medical interventions.
Levamisole HCl, on the other hand, is an immune enhancer and dewormer. Its capacity to enhance the immune system and eliminate parasitic infections differentiates it from Tetracaine. In contrast to Tetracaine, Levamisole HCl is not used for anesthesia. Instead, it plays a key role in managing autoimmune diseases and parasitic infections.
Comparing Levamisole and Procaine
Levamisole and Procaine also have unique medical applications. Procaine, like 99% Procaine Hydrochloride, is a local anesthetic used to bring about temporary numbness in specific areas for procedures such as dental work and minor surgeries. It achieves this by blocking sodium channels, stopping pain signals from arriving at the brain.
Levamisole, however, focuses on boosting the body’s immune response and addressing parasitic worms. This is a big difference from Procaine’s numbing effect. Levamisole does not function as a local anesthetic but supports the body’s defense mechanisms and addresses infections due to parasitic organisms.
Below is a comprehensive differentiation of Levamisole with Tetracaine and Procaine:
| Standard | Levamisole | Tetracaine | Procaine |
|---|---|---|---|
| Main Application | Immune booster and parasitic remover | Pain reliever | Numbing agent |
| Mechanism of Action | Strengthens immune response, eradicates parasites | Stops nerve signals | Inhibits sodium channels |
| Use | Treats Autoimmune Diseases and Parasites | Employed in operations and minor interventions | Applied in dental work and minor surgeries |
Grasping the distinctions between Levamisole HCl, Tetracaine, and Procaine aids medical professionals in choosing the most fit therapy for their patients. This confirms safer and more effective clinical outcomes.
Overview: Pros and Cons of Levamisole HCl
Levamisole Hydrochloride is recognized as a essential drug in human and veterinary medicine. It’s known for its powerful anthelmintic properties, successfully treating parasitic infections. Additionally, it enhances the immune system in some clinical settings, making it a go-to choice for doctors and vets.
However, Levamisole HCl is not without its drawbacks. The list of Levamisole hazards contains adverse reactions that range from mild to severe. While minor issues like nausea and dizziness are tolerable, severe blood disorders demand frequent attention. Thus, a thorough Levamisole review must include both its advantages and its risks.
For those evaluating Levamisole Hydrochloride, a deep grasp is important. Health experts and pet owners must meticulously evaluate the Levamisole benefits against the likely risks. Confirming prudent administration, correct dosing, and vigilant observation is vital. This well-rounded approach is vital for securely and successfully administering Levamisole HCl.